... where LIFE SCIENCE
meets PHYSICS

FSU Jena Kolloquium der Biologisch-Pharmazeutische Fakultät

The main focus of our research is on molecular mechanisms of stem cell aging. Stem cells are present in most adult mammalian tissues and organs and contribute to lifelong maintenance and repair of tissues and organs. In addition, stem cells can represent the cell type of origin of cancer formation. There is emerging evidence that aging alters the self-renewal and the functional capacity of adult stem cells. Understanding the molecular causes of stem cell aging will enable the development of future therapies aiming to improve organ homeostasis and regenerative capacities during aging and to decrease the risk of age-related cancer formation. In my talk, I will present data on DNA damage checkpoint induction in stem cells and its role in aging and cancer.


Back to list